Checkpoint Kinase 1 (CHEK1) (Middle Region) Peptide
CHEK1
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN974903
Aperçu rapide pour Checkpoint Kinase 1 (CHEK1) (Middle Region) Peptide (ABIN974903)
Antigène
CHEK1
(Checkpoint Kinase 1 (CHEK1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- Middle Region
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-CHEK1 antibody (Catalog #: ARP32588_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CHEK1 (Checkpoint Kinase 1 (CHEK1))
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Sujet
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CHEK1 is required during normal S phase to avoid aberrantly increased initiation of DNA replication, thereby protecting against DNA breakage. Its expression is dispensable for somatic cell death and critical for sustaining G2 DNA damage checkpoint.
Alias Symbols: CHK1
Protein Interaction Partner: E2F1,E2F4,ATR,CDC25A,CDC25A,CDC25C,RAD51,RELA,AATF,AKT1,ATM,ATR,BLM,CDC25A,CDC25B,CDC25C,CLSPN,CSNK2B,CUL1,CUL4A,HSP90AA1,MDM4,RAD51,RELA,SMAD4,TLK1,TP53,UBB,XIAP,XRCC6,YWHAG,ATM,ATR,BLM,CDC25A,CDC25B,CDC25C,CDKN1A,CLSPN,CSNK2A1,MCD1,MSH2,PRKDC,SFN,TIMELESS,TP53,TP53BP1,XIAP,XRCC5,XRCC6
Protein Size: 476 -
Poids moléculaire
- 54 kDa
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ID gène
- 1111
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NCBI Accession
- NM_001274, NP_001265
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UniProt
- O14757
Antigène
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