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Checkpoint Kinase 1 (CHEK1) Peptide

CHEK1 Reactivité: Humain Hôte: Synthetic BP, WB, IHC
N° du produit ABIN974904
  • Antigène Tous les produits CHEK1
    CHEK1 (Checkpoint Kinase 1 (CHEK1))
    Origine
    Humain
    Source
    • 16
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-CHEK1 antibody (Catalog #: ARP32589_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    CHEK1 (Checkpoint Kinase 1 (CHEK1))
    Synonymes
    An08g10320 Peptide, AO090003000441 Peptide, CHK1 Peptide, chk1 Peptide, C85740 Peptide, Chk1 Peptide, rad27 Peptide, id:ibd2720 Peptide, zgc:56093 Peptide, CHEK1 Peptide, checkpoint kinase 1 Peptide, serine/threonine-protein kinase chk1 Peptide, serine/threonine-protein kinase Chk1 Peptide, CAMK/CAMKL/CHK1 protein kinase Chk1 Peptide, checkpoint kinase 1 S homeolog Peptide, CHEK1 Peptide, ANI_1_2436074 Peptide, AOR_1_768154 Peptide, PTRG_04183 Peptide, SJAG_01680 Peptide, PAAG_04978 Peptide, MCYG_03290 Peptide, VDBG_03742 Peptide, chek1.S Peptide, Chek1 Peptide, chek1 Peptide
    Sujet
    CHEK1 is required during normal S phase to avoid aberrantly increased initiation of DNA replication, thereby protecting against DNA breakage. Its expression is dispensable for somatic cell death and critical for sustaining G2 DNA damage checkpoint.

    Alias Symbols: CHK1

    Protein Interaction Partner: E2F1,E2F4,ATR,CDC25A,CDC25A,CDC25C,RAD51,RELA,AATF,AKT1,ATM,ATR,BLM,CDC25A,CDC25B,CDC25C,CLSPN,CSNK2B,CUL1,CUL4A,HSP90AA1,MDM4,RAD51,RELA,SMAD4,TLK1,TP53,UBB,XIAP,XRCC6,YWHAG,ATM,ATR,BLM,CDC25A,CDC25B,CDC25C,CDKN1A,CLSPN,CSNK2A1,MCD1,MSH2,PRKDC,SFN,TIMELESS,TP53,TP53BP1,XIAP,XRCC5,XRCC6

    Protein Size: 476
    Poids moléculaire
    54 kDa
    ID gène
    1111
    NCBI Accession
    NM_001274, NP_001265
    UniProt
    O14757
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