Deleted in Azoospermia-Like (DAZL) Peptide
DAZL
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN975602
Aperçu rapide pour Deleted in Azoospermia-Like (DAZL) Peptide (ABIN975602)
Antigène
DAZL
(Deleted in Azoospermia-Like (DAZL))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-DAZL antibody (Catalog #: ARP40356_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Deleted in Azoospermia-Like (DAZL) peptide
DAZL Reactivité: Humain, Souris, Boeuf (Vache), Chien, Rat Hôte: Synthetic BP, Imm
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DAZL (Deleted in Azoospermia-Like (DAZL))
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Sujet
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DAZ (Deleted in AZoospermia) is the potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. DAZL is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of the autosomal gene encoding DAZL during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in the Dazl gene have been linked to severe spermatogenic failure and infertility in males.The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DAZH, DAZL1, DAZLA, MGC26406, SPGYLA
Protein Interaction Partner: DAZ1,DAZ4,DAZAP1,DAZAP2,DAZL,PUM2,DAZ1,DAZAP1,DAZAP2,DAZL
Protein Size: 295 -
Poids moléculaire
- 33 kDa
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ID gène
- 1618
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NCBI Accession
- NM_001351, NP_001342
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UniProt
- Q92904
Antigène
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