IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3) Peptide
IKZF3
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC
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- Antigène Tous les produits IKZF3
- IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-IKZF3 antibody (Catalog #: ARP39004_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
- Synonymes
- AIO Peptide, AIOLOS Peptide, ZNFN1A3 Peptide, aio Peptide, aiolos Peptide, znfn1a3 Peptide, IKZF3 Peptide, 5830411O07Rik Peptide, Aiolos Peptide, Zfpn1a3 Peptide, Znfn1a3 Peptide, IKAROS family zinc finger 3 Peptide, IKAROS family zinc finger 3 L homeolog Peptide, IKZF3 Peptide, ikzf3.L Peptide, Ikzf3 Peptide
- Sujet
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IKZF3 is a member of the Ikaros family of zinc-finger proteins. It is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers.This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoetic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
Alias Symbols: AIO, AIOLOS, ZNFN1A3
Protein Interaction Partner: BCL2L1,CHD3,HRAS,IKZF1,IKZF3,IKZF4,IKZF5,RBBP8,UBE2I,BCL2L1,CHD4,HDAC2,HDAC4,HDAC5,HDAC7,HRAS,IKZF2,IKZF4,IKZF5,SIN3A,SIN3B,UBE2I
Protein Size: 453 - Poids moléculaire
- 52 kDa
- ID gène
- 22806
- NCBI Accession
- NM_183228, NP_899051
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