IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3) Peptide
IKZF3
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN978467
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 22 jours ouvrables
Aperçu rapide pour IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3) Peptide (ABIN978467)
Antigène
IKZF3
(IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-IKZF3 antibody (Catalog #: ARP39005_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))
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Sujet
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IKZF3 is a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoetic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
Alias Symbols: AIOLOS, ZNFN1A3, AIO
Protein Interaction Partner: BCL2L1,CHD3,HRAS,IKZF1,IKZF3,IKZF4,IKZF5,RBBP8,UBE2I,BCL2L1,CHD4,HDAC2,HDAC4,HDAC5,HDAC7,HRAS,IKZF2,IKZF4,IKZF5,SIN3A,SIN3B,UBE2I
Protein Size: 509 -
Poids moléculaire
- 58 kDa
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ID gène
- 22806
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NCBI Accession
- NM_012481, NP_036613
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UniProt
- Q9UKT9
Antigène
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