Transcription Factor B2, Mitochondrial (TFB2M) Peptide
TFB2M
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN984988
Aperçu rapide pour Transcription Factor B2, Mitochondrial (TFB2M) Peptide (ABIN984988)
Antigène
TFB2M
(Transcription Factor B2, Mitochondrial (TFB2M))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-TFB2M antibody (Catalog #: ARP34471_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Transcription Factor B2, Mitochondrial (TFB2M) peptide
TFB2M Reactivité: Humain Hôte: Synthetic BP, Imm
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))
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Sujet
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TFB2M is a S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. It is also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. It stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
Alias Symbols: FLJ22661, FLJ23182, Hkp1, mtTFB2
Protein Interaction Partner: PNP,POLRMT,TFAM,TFB2M,TFAM
Protein Size: 396 -
Poids moléculaire
- 45 kDa
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ID gène
- 64216
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NCBI Accession
- NM_022366, NP_071761
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UniProt
- Q9H5Q4
Antigène
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