Timeless Homolog (TIMELESS) Peptide
TIMELESS
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN985092
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 22 jours ouvrables
Aperçu rapide pour Timeless Homolog (TIMELESS) Peptide (ABIN985092)
Antigène
TIMELESS
(Timeless Homolog (TIMELESS))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-TIMELESS antibody (Catalog #: ARP38403_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TIMELESS (Timeless Homolog (TIMELESS))
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Sujet
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The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein.
Alias Symbols: TIM, TIM1, hTIM
Protein Interaction Partner: CRY1,PER1,PER2,TIPIN,ATRIP,CHEK1,CLSPN,CRY2,Clock,PCNA,Per1,Per2,TIPIN,per
Protein Size: 1208 -
Poids moléculaire
- 139 kDa
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ID gène
- 8914
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NCBI Accession
- NM_003920, NP_003911
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UniProt
- Q9UNS1
Antigène
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