PHLPP2 Protéines
(PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2))
Protein phosphatase that mediates dephosphorylation of 'Ser-473' of AKT1, 'Ser-660' of PRKCB isoform beta-II and 'Ser- 657' of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradation. Inhibits cancer cell proliferation and may act as a tumor suppressor.
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custom-made
PHLPP2
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
PHLPP2
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
PHLPP2
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
1 image
custom-made
PHLPP2
Origine: Souris
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, ELISA, SDS
custom-made
PHLPP2
Origine: Humain
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, ELISA, SDS
PHLPP2
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Rockland 009-001-s91s
PHLPP2
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
>95%
WB
Rockland Original
Pseudonymes pour PHLPP2 Protéines
PH domain and leucine rich repeat protein phosphatase 2 (PHLPP2) ProtéinesPH domain and leucine rich repeat protein phosphatase 2 S homeolog (phlpp2.S) Protéines
PH domain and leucine rich repeat protein phosphatase 2 (phlpp2) Protéines
PH domain and leucine rich repeat protein phosphatase 2 (Phlpp2) Protéines
AI481772 Protéines
C130044A18Rik Protéines
PHLPPL Protéines
phlppl Protéines
Phlppl Protéines
RGD1562857 Protéines
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