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PHLPP2 Protéines

(PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2))
Protein phosphatase that mediates dephosphorylation of 'Ser-473' of AKT1, 'Ser-660' of PRKCB isoform beta-II and 'Ser- 657' of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradation. Inhibits cancer cell proliferation and may act as a tumor suppressor.

7 Résultats

custom-made PHLPP2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
N° du produit ABIN7554929
 
custom-made PHLPP2 Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
N° du produit ABIN7564455
 
PHLPP2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
N° du produit ABIN7124383
 
custom-made PHLPP2 Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, ELISA, SDS
N° du produit ABIN3136302
 
custom-made PHLPP2 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, ELISA, SDS
N° du produit ABIN3094545
 
PHLPP2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2728850
 
Rockland 009-001-s91s PHLPP2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant >95% WB
N° du produit ABIN6700358
Rockland Original
  • Type Protein
    • Protein
  • Application
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Antibody Production (AbP)
    • Standard (STD)
  • Réactivité
    • Human
    • Mouse
  • Images disponible
  • Carrier free only
  • Hote
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Escherichia coli (E. coli)
  • Epitope
    • AA 1-1320
    • AA 1-1323
    • AA 766-1043
  • Conjugué
    • His tag
    • Strep Tag
    • GST tag
    • His-IF2DI Tag
    • Myc-DYKDDDDK Tag
  • Type Proteine
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • custom-made
  • Supplier
    • antibodies-online
    • OriGene
    • Rockland

Pseudonymes pour PHLPP2 Protéines

PH domain and leucine rich repeat protein phosphatase 2 (PHLPP2) Protéines
PH domain and leucine rich repeat protein phosphatase 2 S homeolog (phlpp2.S) Protéines
PH domain and leucine rich repeat protein phosphatase 2 (phlpp2) Protéines
PH domain and leucine rich repeat protein phosphatase 2 (Phlpp2) Protéines
AI481772 Protéines
C130044A18Rik Protéines
PHLPPL Protéines
phlppl Protéines
Phlppl Protéines
RGD1562857 Protéines
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