PLAU Protéines
(Plasminogen Activator, Urokinase (PLAU))
This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009].
| Catalog no. | Produit | Reactivité | Hôte / Clonalité | Application | Prix et délai de livraison |
|---|---|---|---|---|---|
| PLAU Protein (His tag) | Lapin | Escherichia coli (E. coli) |
|
628,83 €
Voir le prix
|
|
| PLAU Protein (His tag) | Poulet | Escherichia coli (E. coli) |
|
628,83 €
Voir le prix
|
|
| PLAU Protein (Transcript Variant 1) (His tag) | Humain | HEK-293 Cells |
|
469,23 €
Voir le prix
|
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- Origine
- Lapin
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 90 %
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- Origine
- Poulet
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 90 %
Protein
- AbP (Antibody Production: Application indiquée)
- STD (Standard: Application indiquée)
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
Dernières publications pour nos PLAU Protéines
: "Quantification of Circulating Cancer Biomarkers via Sensitive Topographic Measurements on Single Binder Nanoarrays." dans: ACS omega, Vol. 2, Issue 6, pp. 2618-2629, (2017) (PubMed).
: "Conserved Amblyomma americanum tick Serpin19, an inhibitor of blood clotting factors Xa and XIa, trypsin and plasmin, has anti-haemostatic functions." dans: International journal for parasitology, Vol. 45, Issue 9-10, pp. 613-27, (2015) (PubMed).
: "Urokinase-type plasminogen activator promotes dendritic spine recovery and improves neurological outcome following ischemic stroke." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 43, pp. 14219-32, (2014) (PubMed).
: "Active ?-macroglobulin is a reservoir for urokinase after fibrinolytic therapy in rabbits with tetracycline-induced pleural injury and in human pleural fluids." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 305, Issue 10, pp. L682-92, (2013) (PubMed).
: "A key role for the urokinase plasminogen activator (uPA) in invasive Group A streptococcal infection." dans: PLoS pathogens, Vol. 9, Issue 7, pp. e1003469, (2013) (PubMed).
: "Domain 2 of uPAR regulates single-chain urokinase-mediated angiogenesis through ?1-integrin and VEGFR2." dans: American journal of physiology. Heart and circulatory physiology, Vol. 305, Issue 3, pp. H305-20, (2013) (PubMed).
: "uPA and uPA-receptor are involved in cancer-associated myeloid-derived suppressor cell accumulation." dans: Anticancer research, Vol. 32, Issue 10, pp. 4263-70, (2012) (PubMed).
: "Targeting tumor cell invasion and dissemination in vivo by an aptamer that inhibits urokinase-type plasminogen activator through a novel multifunctional mechanism." dans: Molecular cancer research : MCR, Vol. 10, Issue 12, pp. 1532-43, (2012) (PubMed).
: "Macrophage-specific expression of urokinase-type plasminogen activator promotes skeletal muscle regeneration." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 3, pp. 1448-57, (2011) (PubMed).
: "Elucidation of the contribution of active site and exosite interactions to affinity and specificity of peptidylic serine protease inhibitors using non-natural arginine analogs." dans: Molecular pharmacology, Vol. 80, Issue 4, pp. 585-97, (2011) (PubMed).
: "Conserved Amblyomma americanum tick Serpin19, an inhibitor of blood clotting factors Xa and XIa, trypsin and plasmin, has anti-haemostatic functions." dans: International journal for parasitology, Vol. 45, Issue 9-10, pp. 613-27, (2015) (PubMed).
: "Urokinase-type plasminogen activator promotes dendritic spine recovery and improves neurological outcome following ischemic stroke." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 43, pp. 14219-32, (2014) (PubMed).
: "Active ?-macroglobulin is a reservoir for urokinase after fibrinolytic therapy in rabbits with tetracycline-induced pleural injury and in human pleural fluids." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 305, Issue 10, pp. L682-92, (2013) (PubMed).
: "A key role for the urokinase plasminogen activator (uPA) in invasive Group A streptococcal infection." dans: PLoS pathogens, Vol. 9, Issue 7, pp. e1003469, (2013) (PubMed).
: "Domain 2 of uPAR regulates single-chain urokinase-mediated angiogenesis through ?1-integrin and VEGFR2." dans: American journal of physiology. Heart and circulatory physiology, Vol. 305, Issue 3, pp. H305-20, (2013) (PubMed).
: "uPA and uPA-receptor are involved in cancer-associated myeloid-derived suppressor cell accumulation." dans: Anticancer research, Vol. 32, Issue 10, pp. 4263-70, (2012) (PubMed).
: "Targeting tumor cell invasion and dissemination in vivo by an aptamer that inhibits urokinase-type plasminogen activator through a novel multifunctional mechanism." dans: Molecular cancer research : MCR, Vol. 10, Issue 12, pp. 1532-43, (2012) (PubMed).
: "Macrophage-specific expression of urokinase-type plasminogen activator promotes skeletal muscle regeneration." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 3, pp. 1448-57, (2011) (PubMed).
: "Elucidation of the contribution of active site and exosite interactions to affinity and specificity of peptidylic serine protease inhibitors using non-natural arginine analogs." dans: Molecular pharmacology, Vol. 80, Issue 4, pp. 585-97, (2011) (PubMed).
Pseudonymes pour PLAU Protéines
plasminogen activator, urokinase (PLAU) Protéinesurokinase-type plasminogen activator (CpipJ_CPIJ002131) Protéines
urokinase-type plasminogen activator (CpipJ_CPIJ006543) Protéines
urokinase-type plasminogen activator (CpipJ_CPIJ013396) Protéines
urokinase-type plasminogen activator (CpipJ_CPIJ013623) Protéines
plasminogen activator, urokinase (Plau) Protéines
ATF Protéines
BDPLT5 Protéines
PLAU Protéines
QPD Protéines
u-PA Protéines
UPA Protéines
uPA Protéines
UPAM Protéines
URK Protéines
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