PNKP Anticorps

Maertens, Kuzmickas, Manchester, Emerson, Gavin, Guild, Wong, De Raedt, Bowman-Colin, Hatchi, Garraway, Flaherty, Pathania, Elledge, Cichowski: "MAPK Pathway Suppression Unmasks Latent DNA Repair Defects and Confers a Chemical Synthetic Vulnerability in BRAF-, NRAS-, and NF1-Mutant Melanomas." dans: Cancer discovery, Vol. 9, Issue 4, pp. 526-545, (2019) (PubMed).

Yip, Keszei, Feng, Chu, McKenna, Shao: "Mechanism for recycling tRNAs on stalled ribosomes." dans: Nature structural & molecular biology, Vol. 26, Issue 5, pp. 343-349, (2019) (PubMed).

Gao, Chakraborty, Geater, Pradhan, Gordon, Snowden, Yuan, Dickey, Choudhary, Ashizawa, Ellerby, La Spada, Thompson, Hazra, Sarkar: "Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription." dans: eLife, Vol. 8, (2019) (PubMed).

Zagorac, Fernandez-Gaitero, Penning, Post, Bueno, Mouron, Manso, Morente, Alonso, Serra, Muñoz, Gómez-López, Lopez-Acosta, Jimenez-Renard, Gris-Oliver, Al-Shahrour, Piñeiro-Yañez, Montoya-Suarez et al.: "In vivo phosphoproteomics reveals kinase activity profiles that predict treatment outcome in triple-negative breast cancer. ..." dans: Nature communications, Vol. 9, Issue 1, pp. 3501, (2018) (PubMed).

Zhang, Sun, Ye, Ashraf, Chen, Zhu, He, Xu, Wei, Chen, Fu, Liu, Cao: "Quantitative Label-Free Phosphoproteomics Reveals Differentially Regulated Protein Phosphorylation Involved in West Nile Virus-Induced Host Inflammatory Response." dans: Journal of proteome research, Vol. 14, Issue 12, pp. 5157-68, (2016) (PubMed).

Markkanen, Fischer, Ledentcova, Kessler, Dianov: "Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability." dans: Nucleic acids research, Vol. 43, Issue 7, pp. 3667-79, (2015) (PubMed).

Shimada, Dumitrache, Russell, McKinnon: "Polynucleotide kinase-phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability." dans: The EMBO journal, Vol. 34, Issue 19, pp. 2465-80, (2015) (PubMed).

Mani, Karimi-Busheri, Fanta, Cass, Weinfeld: "Spectroscopic studies of DNA and ATP binding to human polynucleotide kinase: evidence for a ternary complex." dans: Biochemistry, Vol. 42, Issue 41, pp. 12077-84, (2003) (PubMed).

Chappell, Hanakahi, Karimi-Busheri, Weinfeld, West: "Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining." dans: The EMBO journal, Vol. 21, Issue 11, pp. 2827-32, (2002) (PubMed).

Jilani, Ramotar, Slack, Ong, Yang, Scherer, Lasko: "Molecular cloning of the human gene, PNKP, encoding a polynucleotide kinase 3'-phosphatase and evidence for its role in repair of DNA strand breaks caused by oxidative damage." dans: The Journal of biological chemistry, Vol. 274, Issue 34, pp. 24176-86, (1999) (PubMed).