Proprotein Convertase Subtilisin/kexin Type 9 Anticorps

Lebeau, Platko, Al-Hashimi, Byun, Lhoták, Holzapfel, Gyulay, Igdoura, Cool, Trigatti, Seidah, Austin: "Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained." dans: The Journal of biological chemistry, Vol. 293, Issue 19, pp. 7329-7343, (2019) (PubMed).

Tanaka, Inuzuka, Iida, Shimizu, Unno, Urano: "Proprotein Convertase Subtilisin/Kexin Type 9 Is Associated with Degenerating Adipocytes in Abdominal Aortic Aneurysm." dans: Journal of oleo science, Vol. 67, Issue 10, pp. 1355-1360, (2018) (PubMed).

Jia, Song, Yang, Ma, Li, Lu, Cao, Zhang, Zhu, Wang, Leng, Cao, Du, Xu: "Effects of Tanshinone IIA on the modulation of miR‑33a and the SREBP‑2/Pcsk9 signaling pathway in hyperlipidemic rats." dans: Molecular medicine reports, Vol. 13, Issue 6, pp. 4627-35, (2016) (PubMed).

Lebeau, Al-Hashimi, Sood, Lhoták, Yu, Gyulay, Paré, Chen, Trigatti, Prat, Seidah, Austin: "Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism." dans: The Journal of biological chemistry, Vol. 292, Issue 4, pp. 1510-1523, (2016) (PubMed).

Dubé, Ethier-Chiasson, Lafond: "Modulation of cholesterol transport by insulin-treated gestational diabetes mellitus in human full-term placenta." dans: Biology of reproduction, Vol. 88, Issue 1, pp. 16, (2013) (PubMed).

Diebold, Petry, Hess, Görlach: "The NADPH oxidase subunit NOX4 is a new target gene of the hypoxia-inducible factor-1." dans: Molecular biology of the cell, Vol. 21, Issue 12, pp. 2087-96, (2010) (PubMed).

Brulhart-Meynet, Deakin, Sgroi, Buhler, James: "Expression of the hepatic Niemann-Pick C1 like 1 protein gene is sensitive to rosuvastatin treatment of primary human hepatocytes." dans: Pharmacogenetics and genomics, Vol. 20, Issue 7, pp. 455-8, (2010) (PubMed).

Kwon, Lagace, McNutt, Horton, Deisenhofer: "Molecular basis for LDL receptor recognition by PCSK9." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 6, pp. 1820-5, (2008) (PubMed).

Lambert, Ancellin, Charlton, Comas, Pilot, Keech, Patel, Sullivan, Cohn, Rye, Barter: "Plasma PCSK9 concentrations correlate with LDL and total cholesterol in diabetic patients and are decreased by fenofibrate treatment." dans: Clinical chemistry, Vol. 54, Issue 6, pp. 1038-45, (2008) (PubMed).

Dewpura, Raymond, Hamelin, Seidah, Mbikay, Chrétien, Mayne: "PCSK9 is phosphorylated by a Golgi casein kinase-like kinase ex vivo and circulates as a phosphoprotein in humans." dans: The FEBS journal, Vol. 275, Issue 13, pp. 3480-93, (2008) (PubMed).