RPA3 Protein (AA 1-119, partial) (His tag)

N° du produit ABIN1047599

Cette protéine Recombinant RPA3 est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour RPA3 Protein (AA 1-119, partial) (His tag) (ABIN1047599)

Antigène: RPA3 (Replication Protein A3, 14kDa (RPA3))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS), ELISA

Pureté: 95 %

Détail du produit

Attributs du protein: AA 1-119, partial

Purification/Conjugué: Cette RPA3 protéine est marqué à la His tag.

Séquence: MVDMMDLPRS RINAGMLAQF IDKPVCFVGR LEKIHPTGKM FILSDGEGKN GTIELMEPLD EEISGIVEVV GRVTAKATIL CTSYVQFKED SHPFDLGLYN EAVKIIHDFP QFYPLGIVQ

Specificité: N-terminal 6xHis-tagged

Attributs du produit: Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Ref.7 Ref.9 Functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair, it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. Ref.7 Ref.9

Information d'application

Commentaires:

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Restrictions: For Research Use only

Stockage

Format: Lyophilized or Liquid

Buffer: Liquid protein in buffer: 10 mM Tris-HCl, 1 mM EDTA, pH 8.0,50% glycerol

Stock: -20 °C

Détail du antigène

Antigène: RPA3 (Replication Protein A3, 14kDa (RPA3))

Autre désignation: Replication protein A 14 kDa subunit

Sujet: Synonyms: Replication factor A protein 3

Poids moléculaire: 17.4 kD

UniProt: P35244

Pathways: Telomere Maintenance, Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA