Cathepsin Z Protein (CTSZ) (AA 24-303) (His tag)
Aperçu rapide pour Cathepsin Z Protein (CTSZ) (AA 24-303) (His tag) (ABIN1096251)
Antigène
Voir toutes Cathepsin Z (CTSZ) ProtéinesType de proteíne
Origine
Source
Pureté
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Attributs du protein
- AA 24-303
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Purification/Conjugué
- Cette Cathepsin Z protéine est marqué à la His tag.
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Fonction
- Recombinant Human Cathepsin Z/CTSZ (C-6His)
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Séquence
- GLYFRRGQTC YRPLRGDGLA PLGRSTYPRP HEYLSPADLP KSWDWRNVDG VNYASITRNQ HIPQYCGSCW AHASTSAMAD RINIKRKGAW PSTLLSVQNV IDCGNAGSCE GGNDLSVWDY AHQHGIPDET CNNYQAKDQE CDKFNQCGTC NEFKECHAIR NYTLWRVGDY GSLSGREKMM AEIYANGPIS CGIMATERLA NYTGGIYAEY QDTTYINHVV SVAGWGISDG TEYWIVRNSW GEPWGERGWL RIVTSTYKDG KGARYNLAIE EHCTFGDPIV VDHHHHHH
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Attributs du produit
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Recombinant Human Cathepsin Z/CTSZ (C-6His)
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH 4.0.
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Conseil sur la manipulation
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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Stock
- -80 °C
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Stockage commentaire
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. -
Date de péremption
- 6 months
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- Cathepsin Z (CTSZ)
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Autre désignation
- Cathepsin Z
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Sujet
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Recombinant Human Cathepsin Z produced by transfected human cells is a secreted protein with sequence (Gly24-Val303) of Human CTSZ fused with a polyhistidine tag at the C-terminus.
Cathepsin Z is a lysosomal cysteine proteinase and belongs to the peptidase C1 family. Human Cathepsin Z contains a singnal sequence, a propeptide and a mature chain. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. In contrast to cathepsin B, it does not act as an endopeptidase. Cathepsin Z is restricted to the cells of theimmune system, predominantly monocytes, macrophages and dendritic cells. It is expressed ubiquitously in cancer cell lines and primary tumors. Like other members of this family, Cathepsin Z may be involved in tumorigenesis. -
Poids moléculaire
- 32.51 kDa
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UniProt
- Q9UBR2
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Pathways
- Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
Antigène
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