CXCL10 Protein (AA 22-98)
Aperçu rapide pour CXCL10 Protein (AA 22-98) (ABIN1096459)
Antigène
Voir toutes CXCL10 ProtéinesType de proteíne
Activité biologique
Origine
Source
Application
Pureté
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Attributs du protein
- AA 22-98
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Fonction
- Recombinant Human C-X-C Motif Chemokine 10/CXCL10
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Séquence
- VPLSRTVRCT CISISNQPVN PRSLEKLEII PASQFCPRVE IIATMKKKGE KRCLNPESKA IKNLLKAVSK ERSKRSP
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Attributs du produit
- Recombinant Human C-X-C Motif Chemokine Ligand 10/CXCL10 is produced by E. coli transformed with a plasmid containing sequence (Val22-Pro98) of Human CXCL10.
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Commentaires
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Biological activity: ED50 is 0.02-0.06 µg/mL as determined by the ability of Recombinant CXCL10 to chemoattract human CXCR3 transfected BaF3 mouse proB cells.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.0.
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Conseil sur la manipulation
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
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Stock
- 4 °C/-20 °C/-80 °C
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Stockage commentaire
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. -
Date de péremption
- 3 months
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- CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
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Autre désignation
- ip-10
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Sujet
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Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-gamma. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles, such as chemoattraction for activated T-lymphocytes, inhibition of angiogenesis, and antitumor activity.
Alternative Names: C-X-C Motif Chemokine 10, 10 kDa Interferon Gamma-Induced Protein, Gamma-IP10, IP-10, Small-Inducible Cytokine B10, CXCL10, INP10, SCYB10 -
Poids moléculaire
- 8.6 kDa
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UniProt
- P02778
Antigène
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