SH3G2 Protein (His tag)

N° du produit ABIN1098256

Protéine Recombinant SH3G2 exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour SH3G2 Protein (His tag) (ABIN1098256)

Antigène: SH3G2 (Endophilin-A1 (SH3G2))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Pureté: > 90 % by SDS - PAGE

Détail du produit

Purification/Conjugué: Cette SH3G2 protéine est marqué à la His tag.

Purification: purified by chromatography

Information d'application

Commentaires:

Synonyms: Endophilin-A1, CNSA2, EEN-B1, SH3D2A, SH3P4

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer, pH 8.0, 10% glycerol, 1 MM DTT, 50 mM NaCl

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: SH3G2 (Endophilin-A1 (SH3G2))

Autre désignation: SH3GL2

Sujet: SH3GL2 (SH3-domain GRB2-like 2), also known as endophilin-A1, belongs to the endophilin family. It contains a BAR domain and a SH3 domain. Members of the BAR domain protein superfamily are essential elements of cellular traffic. Endophilins are among the best studied BAR domain proteins. They have a prominent function in synaptic vesicle endocytosis (SVE), receptor trafficking and apoptosis, and in other processes that require remodeling of the membrane structure. SH3GL2 a novel tumor suppressor gene in laryngeal squamous cell carcinoma (LSCC), induces apoptosis of tumor cells by regulating intra-cellular signal transduction networks. Recombinant human SH3GL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 42.5 kDa (376aa) confirmed by MALDI-TOF

NCBI Accession: NP_003017

Pathways: Neurotrophin Signaling Pathway, EGFR Downregulation