GPR177/WLS Protein (AA 101-232) (His tag)

N° du produit ABIN1098794

Cette protéine Recombinant GPR177/WLS est produite dans Escherichia coli (E. coli).

Aperçu rapide pour GPR177/WLS Protein (AA 101-232) (His tag) (ABIN1098794)

Antigène: GPR177/WLS (WLS) (Wntless Homolog (WLS))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Pureté: > 90 %

Détail du produit

Attributs du protein: AA 101-232

Purification/Conjugué: Cette GPR177/WLS protéine est marqué à la His tag.

Séquence: MGSSHHHHHH SSGLVPRGSH MGSMEMSPWF QFMLFILQLD IAFKLNNQIR ENAEVSMDVS LAYRDDAFAE WTEMAHERVP RKLKCTFTSP KTPEHEGRYY ECDVLPFMEI GSVAHKFYLL NIRLPVNEKK KINVGIGEIK DIRLVGIHQN GGFTK

Purification: > 90% by SDS-PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: GPR177/WLS (WLS) (Wntless Homolog (WLS))

Autre désignation: GPR177/WLS

Sujet: WLS, a Wnt trafficking regulator, is a multipass transmembrane protein that regulates the sorting and secretion of Wnt protein. It is required for organogenesis during embryogenesis and for the establishment of the anterior-posterior axis. WLS promotes various cancers such as glioma tumourigenesis. The gene encoding WLS maps to human chromosome 1 and is expressed as multiple alternatively spliced isoforms. Recombinant human WLS protein, fused to His-tag at N-terminus, was expressed in E. coli.

Poids moléculaire: 17.8 kDa (155aa)

NCBI Accession: NP_079187

Pathways: Signalisation WNT