DCK Protein (AA 1-260) (His-T7)
Aperçu rapide pour DCK Protein (AA 1-260) (His-T7) (ABIN1691941)
Antigène
Voir toutes DCK ProtéinesType de proteíne
Origine
Source
Pureté
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Attributs du protein
- AA 1-260
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Purification/Conjugué
- Cette DCK protéine est marqué à la His-T7.
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Fonction
- Recombinant Human Deoxycytidine Kinase/DCK (N-6His, T7 tag)
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Séquence
- MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSMATPPK RSCPSFSASS EGTRIKKISI EGNIAAGKST FVNILKQLCE DWEVVPEPVA RWCNVQSTQD EFEELTMSQK NGGNVLQMMY EKPERWSFTF QTYACLSRIR AQLASLNGKL KDAEKPVLFF ERSVYSDRYI FASNLYESEC MNETEWTIYQ DWHDWMNNQF GQSLELDGII YLQATPETCL HRIYLRGRNE EQGIPLEYLE KLHYKHESWL LHRTLKTNFD YLQEVPILTL DVNEDFKDKY ESLVEKVKEF LSTL
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Attributs du produit
- Recombinant Human Deoxycytidine Kinase is produced by our E.coli expression system and the target gene encoding Met1-Leu260 is expressed with a 6His, T7 tag at the N-terminus.
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
Buffer
- Supplied as a 0.2 um filtered solution of 20 mM Tris-HCl, pH 7.5.
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Conseil sur la manipulation
- minimize freeze-thaw cycles
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Stock
- -20 °C
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Stockage commentaire
- Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
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Date de péremption
- 6 months
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- DCK (Deoxycytidine Kinase (DCK))
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Autre désignation
- DCK
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Sub Type
- Fusionprotein
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Sujet
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Alternative Names: Deoxycytidine Kinase, dCK, DCKDeoxycytidine Kinase (DCK) is a member of the DCK/DGK family. DCK exists as a homodimer and is localized to the nucleus. DCK is required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG), and deoxyadenosine (dA). DCK has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. In addition, DCK is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents. DCK is clinically important because of its relationship to drug resistance and sensitivity.
Alternative Names: Deoxycytidine Kinase, dCK, DCK -
Poids moléculaire
- 34 kDa
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UniProt
- P27707
Antigène
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