CD72 Protein (AA 117-226) (His-TRX)
Aperçu rapide pour CD72 Protein (AA 117-226) (His-TRX) (ABIN1691965)
Antigène
Voir toutes CD72 ProtéinesType de proteíne
Origine
Source
Pureté
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Attributs du protein
- AA 117-226
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Purification/Conjugué
- Cette CD72 protéine est marqué à la His-TRX.
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Fonction
- Recombinant Human B-Cell Differentiation Antigen CD72/Lyb-2 (N-Trx, 6His)
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Séquence
- MSDKIIHLTD DSFDTDVLKA DGAILVDFWA EWCGPCKMIA PILDEIADEY QGKLTVAKLN IDQNPGTAPK YGIRGIPTLL LFKNGEVAAT KVGALSKGQL KEFLDANLAG SGSGHMHHHH HHSSGLVPRG SGMKETAAAK FERQHMDSPD LGTDDDDKAM ADIGSMRYLQ VSQQLQQTNR VLEVTNSSLR QQLRLKITQL GQSAEDLQGS RRELAQSQEA LQVEQRAHQA AEGQLQACQA DRQKTKETLQ SEEQQRRALE QKLSNMENRL KPFFTC
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Attributs du produit
- Recombinant Human B-Cell Differentiation Antigen CD72 is produced by our E.coli expression system and the target gene encoding Arg117-Cys226 is expressed with a Trx, 6His tag at the N-terminus.
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
Buffer
- Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Date de péremption
- 3 weeks
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- CD72 (CD72 Molecule (CD72))
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Autre désignation
- CD72
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Sujet
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Alternative Names: B-Cell Differentiation Antigen CD72, Lyb-2, CD72B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, monocytes, dendritic cells, and mast cells. CD72 is a ligand for CD5. CD72 associates with CD5, interacts with PTPN6/SHP-1 and plays a role in B-cell proliferation and differentiation. CD72 associates with CD79A in the B cell antigen receptor (BCR) complex following antigen stimulation and dampens BCR signaling through interactions with the phosphatase SHP-1.
Alternative Names: B-Cell Differentiation Antigen CD72, Lyb-2, CD72 -
Poids moléculaire
- 30.6 kDa
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UniProt
- P21854
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Pathways
- BCR Signaling
Antigène
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