IL-21 Protein (AA 23-155)

N° du produit ABIN1880654

Cette protéine Recombinant IL-21 est produite dans Escherichia coli (E. coli).

Aperçu rapide pour IL-21 Protein (AA 23-155) (ABIN1880654)

Antigène: IL-21 (IL21) (Interleukin 21 (IL21))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Attributs du protein: AA 23-155

Fonction: Recombinant Human Interleukin-21/IL-21

Séquence: MQGQDRHMIR MRQLIDIVDQ LKNYVNDLVP EFLPAPEDVE TNCEWSAFSC FQKAQLKSAN TGNNERIINV SIKKLKRKPP STNAGRRQKH RLTCPSCDSY EKKPPKEFLE RFKSLLQKMI HQHLSSRTHG SEDS

Attributs du produit: Recombinant Human Interleukin-21 is produced by our E.coli expression system and the target gene encoding Gln30-Ser162 is expressed.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 um filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Stock: 4 °C,-20 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 weeks

Détail du antigène

Antigène: IL-21 (IL21) (Interleukin 21 (IL21))

Autre désignation: Interleukin-21/IL-21

Sub Type: Fusionprotein

Sujet: Alternative Names: Interleukin-21,IL-21, Za11, IL21IL-21 induces the production of IgG1 and IgG3 in B-cells. IL-21 may promote the transition between innate and adaptive immunity. IL-21 may have a role in proliferation and maturation of natural killer cells in synergy with IL15. IL-21 stimulates interferon gamma production in T-cells and natural killer cells by synergy with IL15 and IL18. Dysregulation of IL-21 has a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases.
Alternative Names: Interleukin-21 (IL-21), also known as Za11, is a member of the IL-15/IL-21 family. IL-21 is expressed in activated CD4-positive T-cells, no expressed in CD8-positive T-cells, B-cells and monocytes.

Poids moléculaire: 15.6 kDa

UniProt: Q9HBE4

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response