BDNF Protein (AA 129-247)
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- Antigène Voir toutes BDNF Protéines
- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 129-247
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Origine
- Humain
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Source
- CHO Cells
- Attributs du produit
- ED50<4 μg/mL, measured in a bioassay using C6 cells.
- Pureté
- > 95 % as analyzed by SDS-PAGE.
- niveau d'endotoxine
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product BDNF Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Stock
- -80 °C
- Stockage commentaire
- Lyophilized recombinant human BDNF remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, human BDNF should be stable up to 1 week at 4°C or up to 2 months at -20°C.
- Date de péremption
- 6 months
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- Antigène
- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
- Autre désignation
- BDNF (BDNF Produits)
- Synonymes
- ANON2 Protein, BULN2 Protein, bdnf-A Protein, BDNF Protein, bdnf Protein, brain derived neurotrophic factor Protein, brain-derived neurotrophic factor Protein, brain-derived neurotrophic factor L homeolog Protein, brain-derived neurotrophic factor S homeolog Protein, BDNF Protein, Bdnf Protein, bdnf Protein, bdnf.L Protein, bdnf.S Protein
- Sujet
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BDNF, also known as brain-derived neurotrophic factor and abrineurin, is a neurotrophin belonging to the NGF-beta family. It is expressed highly in the brain, and moderately in the heart, lung, skeletal muscle and placenta. BDNF signals through its high affinity receptor gp145/trkB to exert neurotrophic properties. It has been shown to be involved in the survival and differentiation of both the central and peripheral nervous system. Specifically, BDNF regulates synaptic transmission, axonal growth and path-finding, as well as dendritic growth and morphology.
Synonyms: brain-derived neurotrophic factor, abrineurin - Poids moléculaire
- 12-14 kDa, observed by reducing SDS-PAGE.
- UniProt
- P23560
- Pathways
- Signalisation RTK, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
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