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IL1A Protein (AA 116-270)

Cette protéine Recombinant IL1A est exprimée dans CHO Cells.
N° du produit ABIN2018084

Aperçu rapide pour IL1A Protein (AA 116-270) (ABIN2018084)

Antigène

Voir toutes IL1A Protéines
IL1A (Interleukin 1 alpha (IL1A))

Type de proteíne

Recombinant

Activité biologique

Active

Origine

  • 21
  • 16
  • 9
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Rat

Source

  • 48
  • 13
  • 11
  • 2
  • 2
  • 2
CHO Cells

Pureté

> 95 % as analyzed by SDS-PAGE.
  • Attributs du protein

    AA 116-270

    Attributs du produit

    ED50 <5 pg/mL, measured in a proliferation assay using D10S cells.

    niveau d'endotoxine

    < 0.2 EU/μg, determined by LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Reconstituted in ddH2O or PBS at 100 μg/mL.

    Buffer

    Lyophilized after extensive dialysis against PBS.

    Stock

    -80 °C

    Stockage commentaire

    Lyophilized recombinant Rat Interleukin-1 alpha remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Rat Interleukin-1 alpha should be stable up to 1 week at 4°C or up to 2 months at -20°C.

    Date de péremption

    6 months
  • Antigène

    IL1A (Interleukin 1 alpha (IL1A))

    Autre désignation

    Interleukin-1alpha (IL-1alpha)

    Sujet

    Interleukin-1 alpha (IL-1α), is produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta bind to the same receptor and have similar if not identical biological properties. These cytokines have a broad range of activities including stimulation of thymocyte proliferation via IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity, and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine.
    Synonyms: Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)

    Poids moléculaire

    17-22 kDa, observed by reducing SDS-PAGE.

    UniProt

    P16598

    Pathways

    Signalisation NF-kappaB, Autophagy, Cancer Immune Checkpoints
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