PDGFD Protein (AA 250-370)

N° du produit ABIN2018314

Cette protéine Recombinant PDGFD est exprimée dans CHO Cells.

Aperçu rapide pour PDGFD Protein (AA 250-370) (ABIN2018314)

Antigène: PDGFD (Platelet Derived Growth Factor D (PDGFD))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: CHO Cells

Pureté: > 95 % as analyzed by SDS-PAGE.

Détail du produit

Attributs du protein: AA 250-370

Attributs du produit: ED50 < 5 μg/mL, measured in a cell proliferation assay using 3T3 cells.

niveau d'endotoxine: < 0.2 EU/μg, determined by LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Stock: -80 °C

Stockage commentaire: Lyophilized recombinant human PDGF-DD remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human PDGF-DDshould be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Date de péremption: 6 months

Détail du antigène

Antigène: PDGFD (Platelet Derived Growth Factor D (PDGFD))

Sujet: PDGF-DD, also known as platelet-derived growth factor D, IEGF and SCDGFB, is asecreted growth factor belonging to the PDGF/VEGFfamily. It is highly expressed in the heart, pancreas, adrenal glands and ovary. PDGF-DD forms functional homodimers that bind and induce PDGF Rbeta homodimers and PDGF R alpha/beta heterodimers that promote intracellular signaling. This plays an important role in the regulation of cell differentiation, migration and survival. It has also been reported that PDGF-DD can induce monocyte and macrophage recruitment, increase interstitial pressure and facilitate wound healing.
Synonyms: platelet-derived growth factor D, IEGF, SCDGFB

Poids moléculaire: 19-21 kDa, observed by reducing SDS-PAGE.

UniProt: Q9GZP0

Pathways: Signalisation RTK, Platelet-derived growth Factor Receptor Signaling