VEGFC Protein (AA 102-227)

N° du produit ABIN2018451

Protéine Recombinant VEGFC exprimée dans HEK-293T Cells.

Aperçu rapide pour VEGFC Protein (AA 102-227) (ABIN2018451)

Antigène: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: HEK-293T Cells

Pureté: > 95 % as analyzed by SDS-PAGE.

Détail du produit

Attributs du protein: AA 102-227

Attributs du produit: Measured in a cell proliferation assay using HMVEC human microvascular endothelial cells. The ED50 for this effect is < 0.5 μg/mL.
AA 102-227 with an N-terminal Met.

niveau d'endotoxine: < 0.2 EU/μg, determined by LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Stock: -80 °C

Stockage commentaire: Lyophilized recombinant Human Vascular Endothelial Growth Factor C remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Vascular Endothelial Growth Factor C should be stable up to 1 week at 4 °C or up to 3 months at -20 °C.

Date de péremption: 6 months

Détail du antigène

Antigène: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Autre désignation: Vascular Endothelial Growth Factor C (VEGF-C)

Sujet: Vascular endothelial growth factor C (VEGF-C) is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis, lymphangiogenesis and endothelial cell growth and survival, and can also affect the permeability of blood vessels. VEGF-C is expressed in various tissues, however it is not produced in peripheral blood lymphocytes. It forms cell surface-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. The structure and function of VEGF-C is similar to those of vascular endothelial growth factor D (VEGF-D).Recombinant human VEGF-C produced in HEK293 cells is a polypeptide chain containing 126 amino acids. A fully biologically active molecule, rhVEGF-C has a molecular mass of 16-19 kDa analyzed by reducing SDS-PAGE.
Synonyms: Flt4 ligand, VRP

Poids moléculaire: 16-19 kDa, observed by reducing SDS-PAGE.

UniProt: P14844

Pathways: Signalisation RTK, Signaling Events mediated by VEGFR1 and VEGFR2