Pleiotrophin Protein (PTN)
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- Antigène Voir toutes Pleiotrophin (PTN) Protéines
- Pleiotrophin (PTN)
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Séquence
- GKKEKPEKKV KKSDCGEWQW SVCVPTSGDC GLGTREGTRT GAECKQTMKT QRCKIPCNWK KQFGAECKYQ FQAWGECDLN TALKTRTGSL KRALHNAECQ KTVTISKPCG KLTKPKPQAE SKKKKKEGKK QEKMLD
- Attributs du produit
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Purified recombinant Human Pleiotrophin protein
Expression System: E.coli - Pureté
- > 98 % pure
- niveau d'endotoxine
- < 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product PTN Protéine
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
- Buffer
- Lyophilized from 5 mM Na3PO4, pH 7.4.
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Antigène
- Pleiotrophin (PTN)
- Autre désignation
- Pleiotrophin (PTN Produits)
- Synonymes
- zHBNF Protein, zgc:111787 Protein, harp Protein, hbnf Protein, X-PTF Protein, hbgf8 Protein, negf1 Protein, ptn Protein, PTN Protein, HARP Protein, HBGF8 Protein, HBNF Protein, NEGF1 Protein, PTN-A Protein, HB-GAM Protein, HBBM Protein, HBGF-8 Protein, OSF-1 Protein, HBBN Protein, OSF Protein, Osf-1 Protein, Osf1 Protein, Hbnf Protein, pleiotrophin Protein, pleiotrophin L homeolog Protein, ptn Protein, PTN Protein, ptn.L Protein, Ptn Protein
- Sujet
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Pleiotrophin and Midkine are structurally related heparin-binding neurotrophic factors, whose expression is developmentally regulated. The expression pattern of these neurotrophic factors suggests function in neurogenesis, cell migration, secondary organogenetic induction, and mesoderm epithelial interaction. The expression of PTN increases during the process of brain embryogenesis and reaches maximum levels at time of birth. The physiological roles of PTN and Midkine are largely unknown, but these neurotrophins have been implicated in the pathogenesis of neuroblastomas.
Alternative Names: HBGF-8 protein, PTN protein, OSF-1 protein, HARP protein, Osteoblast-Specific Factor-1 protein, Heparin-binding growth factor-8protein, Heparin Affin Regulatory Protein protein - Poids moléculaire
- 15.4 kDa
- Pathways
- Signalisation RTK
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