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VEGF 165 (Active) Protéine

Cette protéine Recombinant VEGF 165 est exprimée dans Escherichia coli (E. coli).
N° du produit ABIN2469210
345,13 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 6 à 9 jours ouvrables

Aperçu rapide pour VEGF 165 (Active) Protéine (ABIN2469210)

Antigène

VEGF 165

Type de proteíne

Recombinant

Activité biologique

Active

Origine

  • 32
  • 3
  • 1
Rat

Source

  • 17
  • 9
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Pureté

< 98 % by SDS-PAGE gel and HPLC analyses.
  • Séquence

    MAPTTEGEQK AHEVVKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNVTMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKHCEPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR

    Attributs du produit

    Biological activity was determined by the dose - dependent stimulation of the proliferation of Human umbilical vein endothelial cells (HUVEC). The expected ED50 is 4.0 - 8.0 ng/mL.

    niveau d'endotoxine

    Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Conseil sur la manipulation

    As with any protein, exposing VEGF165 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

    Stock

    -20 °C

    Stockage commentaire

    The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted VEGF165 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

    Date de péremption

    24 months
  • Antigène

    VEGF 165

    Autre désignation

    VEGF165

    Sujet

    VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothellial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors , fms-like tyrosine kinase(flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant rat VEGF is a 38.5 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.

    ID gène

    83785

    NCBI Accession

    NP_001103803

    OMIM

    160358793
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