Cofilin Protein (Myc-DYKDDDDK Tag)
Aperçu rapide pour Cofilin Protein (Myc-DYKDDDDK Tag) (ABIN2712944)
Antigène
Voir toutes Cofilin (CFL1) ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Purification/Conjugué
- Cette Cofilin protéine est marqué à la Myc-DYKDDDDK Tag.
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Attributs du produit
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- Recombinant human Cofilin-1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Cofilin 1 (CFL1) (AA 2-166) protein (His tag)
CFL1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Cofilin 1 (CFL1) (AA 1-166) protein (GST tag)CFL1 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Cofilin 1 (CFL1) (AA 1-166) protein (His tag)CFL1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Commentaires
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Cofilin (CFL1) (Cofilin 1 (CFL1))
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Autre désignation
- Cofilin-1
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Sujet
- The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH -dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH -dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
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Poids moléculaire
- 18.3 kDa
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NCBI Accession
- NP_005498
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Pathways
- Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
Antigène
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