Apolipoprotein C-II Protein (APOC2) (Myc-DYKDDDDK Tag)
Aperçu rapide pour Apolipoprotein C-II Protein (APOC2) (Myc-DYKDDDDK Tag) (ABIN2714825)
Antigène
Voir toutes Apolipoprotein C-II (APOC2) ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Purification/Conjugué
- Cette Apolipoprotein C-II protéine est marqué à la Myc-DYKDDDDK Tag.
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Attributs du produit
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- Recombinant human Apolipoprotein C II / ApoC2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Commentaires
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC/MS/MS." dans: Journal of lipid research, Vol. 55, Issue 6, pp. 1179-87, (2016) (PubMed).
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: "Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC/MS/MS." dans: Journal of lipid research, Vol. 55, Issue 6, pp. 1179-87, (2016) (PubMed).
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- Apolipoprotein C-II (APOC2)
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Autre désignation
- Apolipoprotein C II (Apo Cii)
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Sujet
- This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene.
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Poids moléculaire
- 8.9 kDa
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NCBI Accession
- NP_000474
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Pathways
- Lipid Metabolism
Antigène
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