Apolipoprotein C-II Protein (APOC2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2714825

Détail du produit

Antigène: Apolipoprotein C-II (APOC2)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Apolipoprotein C-II protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Apolipoprotein C II / ApoC2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Référence

Pan, Zhou, Mahsut, Rohm, Berejnaia, Price, Chen, Castro-Perez, Lassman, McLaren, Conway, Jensen, Thomas, Reyes-Soffer, Ginsberg, Gutstein, Cleary, Previs, Roddy: "Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC/MS/MS." dans: Journal of lipid research, Vol. 55, Issue 6, pp. 1179-87, (2016) (PubMed).

Détail du antigène

Antigène: Apolipoprotein C-II (APOC2)

Autre désignation: Apolipoprotein C II (Apo Cii) (APOC2 Produits)

Synonymes: apoc2 Protein, apoC-II Protein, fb98g08 Protein, wu:fb52e03 Protein, wu:fb71a04 Protein, wu:fb98g08 Protein, APOC2 Protein, APO-CII Protein, APOC-II Protein, RGD1560725 Protein, APOCII Protein, Apo-CII Protein, ApoC-II Protein, apolipoprotein C-II Protein, apolipoprotein C2 Protein, apoc2 Protein, APOC2 Protein, Apoc2 Protein

Sujet: This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene.

Poids moléculaire: 8.9 kDa

NCBI Accession: NP_000474

Pathways: Lipid Metabolism