BID Protein (Transcript Variant 2)
Aperçu rapide pour BID Protein (Transcript Variant 2) (ABIN2715263)
Antigène
Voir toutes BID ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Attributs du protein
- Transcript Variant 2
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Attributs du produit
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- Recombinant human BID (transcript variant 2) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
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niveau d'endotoxine
- < 0.1 EU per μg protein as determined by LAL test
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 20 mM Phosphate buffer, 100 mM KCl, pH 7.4. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- BID (BH3 Interacting Domain Death Agonist (BID))
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Autre désignation
- Bid
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Sujet
- This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8) CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
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Poids moléculaire
- 22 kDa
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NCBI Accession
- NP_001187
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Pathways
- Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
Antigène
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