Endothelin 1 Protein (EDN1) (Myc-DYKDDDDK Tag)
Aperçu rapide pour Endothelin 1 Protein (EDN1) (Myc-DYKDDDDK Tag) (ABIN2720181)
Antigène
Voir toutes Endothelin 1 (EDN1) ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Purification/Conjugué
- Cette Endothelin 1 protéine est marqué à la Myc-DYKDDDDK Tag.
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Attributs du produit
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- Recombinant human Endothelin-1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Commentaires
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Endothelin 1 (EDN1)
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Autre désignation
- Endothelin-1
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Sujet
- This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.
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Poids moléculaire
- 22.4 kDa
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NCBI Accession
- NP_001946
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Pathways
- Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size
Antigène
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