Hexokinase 2 Protein (HK2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2722680

Cette protéine Recombinant Hexokinase 2 est produite dans HEK-293 Cells.

Aperçu rapide pour Hexokinase 2 Protein (HK2) (Myc-DYKDDDDK Tag) (ABIN2722680)

Antigène: Hexokinase 2 (HK2)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Détail du produit

Purification/Conjugué: Cette Hexokinase 2 protéine est marqué à la Myc-DYKDDDDK Tag.

Attributs du produit:

• Recombinant human Hexokinase-2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Hexokinase 2 (HK2)

Autre désignation: Hexokinase-2

Sujet: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Poids moléculaire: 102.2 kDa

NCBI Accession: NP_000180

Pathways: Signalisation PI3K-Akt, Carbohydrate Homeostasis, L'effet Warburg