Ret Proto-Oncogene Protein (RET) (DYKDDDDK Tag)

N° du produit ABIN2730741

Cette protéine Recombinant Ret Proto-Oncogene est produite dans Insect cells (Sf9).

Aperçu rapide pour Ret Proto-Oncogene Protein (RET) (DYKDDDDK Tag) (ABIN2730741)

Antigène: Ret Proto-Oncogene (RET)

Type de proteíne: Recombinant

Origine: Humain

Source: Insect cells (Sf9)

Application: Antibody Production (AbP), Standard (STD)

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Détail du produit

Purification/Conjugué: Cette Ret Proto-Oncogene protéine est marqué à la DYKDDDDK Tag.

Attributs du produit:

• Recombinant human RET (C-term DDK tag, transcript variant 2) protein expressed in sf9 cells.
• Produced with end-sequenced ORF clone

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Ret Proto-Oncogene (RET)

Autre désignation: Ret

Sujet: This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed.

Poids moléculaire: 35.3 kDa

NCBI Accession: NP_066124

Pathways: Signalisation RTK, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation