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SLIT2 Protéine

SLIT2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD, Func, PI Active
N° du produit ABIN2732203
  • Antigène Voir toutes SLIT2 Protéines
    SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Origine
    • 10
    • 5
    • 3
    Humain
    Source
    • 7
    • 6
    • 3
    • 1
    • 1
    HEK-293 Cells
    Application
    Antibody Production (AbP), Standard (STD), Functional Studies (Func), Protein Interaction (PI)
    Specificité
    Optimal preservation of protein structure, post-translational modifications and functions.
    Attributs du produit
    • Recombinant human SLIT2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Pureté
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    niveau d'endotoxine
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Determined by its ability to inhibit MC3T3/E1 osteoblasts cell differentiation.
    Top Product
    Discover our top product SLIT2 Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Restrictions
    For Research Use only
  • Buffer
    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
    Conseil sur la manipulation
    Resuspend the protein in the desired concentration in proper buffer
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))
    Autre désignation
    Slit2 (SLIT2 Produits)
    Synonymes
    SLIL3 Protein, Slit-2 Protein, Drad-1 Protein, E030015M03Rik Protein, E130320P19Rik Protein, Slil3 Protein, mKIAA4141 Protein, Slit Protein, slil3 Protein, slit-2 Protein, slit2-a Protein, SLIT2 Protein, slit guidance ligand 2 Protein, slit homolog 2 (Drosophila) Protein, slit guidance ligand 2 S homeolog Protein, SLIT2 Protein, Slit2 Protein, slit2 Protein, slit2.S Protein
    Sujet
    This gene encodes a member of the slit family of secreted glycoproteins, which are ligands for the Robo family of immunoglobulin receptors. Slit proteins play highly conserved roles in axon guidance and neuronal migration and may also have functions during other cell migration processes including leukocyte migration. Members of the slit family are characterized by an N-terminal signal peptide, four leucine-rich repeats, nine epidermal growth factor repeats, and a C-terminal cysteine knot. Proteolytic processing of this protein gives rise to an N-terminal fragment that contains the four leucine-rich repeats and five epidermal growth factor repeats and a C-terminal fragment that contains four epidermal growth factor repeats and the cysteine knot. Both full length and cleaved proteins are secreted extracellularly and can function in axon repulsion as well as other specific processes. Alternative splicing results in multiple transcript variants.
    Poids moléculaire
    120 kDa
    NCBI Accession
    NP_004778
    Pathways
    Regulation of Actin Filament Polymerization, Regulation of Cell Size, Smooth Muscle Cell Migration
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