PLGF Protéine

N° du produit ABIN2745802

Cette protéine Recombinant PLGF est exprimée dans Insect cells (Sf9).

Aperçu rapide pour PLGF Protéine (ABIN2745802)

Antigène: PLGF (PGF) (Placenta Growth Factor (PGF))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Insect cells (Sf9)

Application: SDS-PAGE (SDS)

Pureté: >95 % (SDS-PAGE)

Détail du produit

Fonction: PLGF (human) (rec.)

Réactivité croisée: Humain

Attributs du produit: Human PLGF (131aa).

Biological Activity Comment: Measured by its ability to bind to immobilized rhsFlt-1 in a functional ELISA. Recombinant human PLGF can bind to immobilized rhsFlt-1 (100ng/well) with a linear range at 0.5-10ng/ml.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with 50 mM acetic acid or PBS/water. This solution can be diluted into other buffered solutions or stored frozen for future use.

Conseil sur la manipulation: After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution.

Stock: 4 °C,-20 °C

Stockage commentaire:

Short Term Storage: +4°C

Long Term Storage: -20°C

Use & Stability: Stable for at least 6 months after receipt when stored at -20°C.

Date de péremption: 6 months

Détail du antigène

Antigène: PLGF (PGF) (Placenta Growth Factor (PGF))

Autre désignation: PLGF

Sujet:

Placenta Growth Factor, PLGF-1, PLGF-131

Human placenta growth factor-1 (PLGF-1, PLGF) binds to the receptor FLT1/VEGFR-1. It acts as a potent chemoattractant for monocytes and only as a very weak mitogen for some endothelial cell types. The physiological function in vivo is still controversial. In several reports it was shown not to be a potent mitogen for endothelial cells and not angiogenic in vivo by using different assays. It was shown that PLGF from cell culture supernatants was angiogenic in the CAM assay and in the rabbit cornea assay.

Poids moléculaire: ~34kDa (dimer)

UniProt: P49763

Pathways: VEGFR1 Specific Signals