VEGF 165 (Active) Protéine

N° du produit ABIN2746011

Détail du produit

Antigène: VEGF 165

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Insect cells (Sf9)

Application: SDS-PAGE (SDS)

Réactivité croisée: Humain

Attributs du produit: Human VEGF 165 (165aa).

Pureté: >95 % (SDS-PAGE)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

The ED50 for stimulation of cell proliferation by human umbilical vein endothelial cells for VEGF 165 has been determined to be in the range of 1-4ng/ml.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with 50 mM acetic acid to a concentration not lower than 50 μg/mL.

Concentration: Lot specific

Buffer: Lyophilized.

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

Date de péremption: 6 months

Détail du antigène

Antigène: VEGF 165

Sujet: Human vascular endothelial growth factor (VEGF 165) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. VEGF 165 is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. In addition to its action as a mitogen it is a potent vascular permeability factor (VPF) in vivo. It is also a chemoattractant molecule for monocytes and endothelial cells. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.

Poids moléculaire: ~45kDa