Indian Hedgehog Protein (IHH)

N° du produit ABIN2830462

Cette protéine Recombinant Indian Hedgehog est produite dans Escherichia coli (E. coli).

Aperçu rapide pour Indian Hedgehog Protein (IHH) (ABIN2830462)

Antigène: Indian Hedgehog (IHH)

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Application: Functional Studies (Func)

Pureté: >96 % as determined by SDS-PAGE and HPLC.

Détail du produit

Séquence: IIGPGRVVGS RRRPPRKLVP LAYKQFSPNV PEKTLGASGR YEGKIARSSE RFKELTPNYN PDIIFKDEEN TGADRLMTQR CKDRLNSLAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY EGRAVDITTS DRDRNKYGLL ARLAVEAGFD WVYYESKAHV HCSVKSEHSA AAKTGG

Attributs du produit: Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to induce alkaline phosphatase production by C3H10T1/2(CCL-226) cells is 3.0-10 μg/mL.

Stérilité: 0.2 μm filtered

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 20 mM PB, pH 7.4, 150 mM NaCl

Stock: -20 °C

Détail du antigène

Antigène: Indian Hedgehog (IHH)

Autre désignation: IHH

Sujet: Relevance: Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity). {ECO:0000250}.
Synonyms: IHH,

Poids moléculaire: 19.8 kDa

UniProt: Q14623

Pathways: Signalisation Hedgehog