Indian Hedgehog Protein (IHH)
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- Antigène Voir toutes Indian Hedgehog (IHH) Protéines
- Indian Hedgehog (IHH)
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func)
- Séquence
- IIGPGRVVGS RRRPPRKLVP LAYKQFSPNV PEKTLGASGR YEGKIARSSE RFKELTPNYN PDIIFKDEEN TGADRLMTQR CKDRLNSLAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY EGRAVDITTS DRDRNKYGLL ARLAVEAGFD WVYYESKAHV HCSVKSEHSA AAKTGG
- Attributs du produit
- Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to induce alkaline phosphatase production by C3H10T1/2(CCL-226) cells is 3.0-10 μg/mL.
- Pureté
- >96 % as determined by SDS-PAGE and HPLC.
- Stérilité
- 0.2 μm filtered
- Top Product
- Discover our top product IHH Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 20 mM PB, pH 7.4, 150 mM NaCl
- Stock
- -20 °C
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- Antigène
- Indian Hedgehog (IHH)
- Autre désignation
- IHH (IHH Produits)
- Synonymes
- BDA1 Protein, HHG2 Protein, X-hh Protein, Xbhh Protein, bhh Protein, bhh-a Protein, IHH Protein, ehh Protein, zgc:113262 Protein, indian hedgehog Protein, Indian hedgehog Protein, indian hedgehog S homeolog Protein, Indian hedgehog homolog b Protein, IHH Protein, Ihh Protein, ihh.S Protein, ihhb Protein
- Sujet
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Relevance: Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity). {ECO:0000250}.
Synonyms: IHH, - Poids moléculaire
- 19.8 kDa
- UniProt
- Q14623
- Pathways
- Signalisation Hedgehog
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