IL-6 Receptor Protein (AA 20-358)

N° du produit ABIN2816729

Cette protéine Recombinant IL-6 Receptor est exprimée dans Baculovirus.

Aperçu rapide pour IL-6 Receptor Protein (AA 20-358) (ABIN2816729)

Antigène: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Baculovirus

Application: Functional Studies (Func)

Pureté: >97 % as determined by SDS-PAGE.

Détail du produit

Attributs du protein: AA 20-358

Séquence: Leu20 - Asp358, Accession # P08887.1

Attributs du produit: Biological Activity: The ED50, as determined by enhancing IL-6 activity using murine M1 cells, is less than 15 ng/mL.

Stérilité: 0.2 μm filtered

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4.

Stock: -20 °C

Détail du antigène

Antigène: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Autre désignation: IL6R

Sujet: Relevance: Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis., Low concentration of a soluble form of IL6 receptor acts as an agonist of IL6 activity.
Synonyms: IL-6 receptor subunit alpha, IL-6R-alpha, IL-6RA, IL-6R 1, Membrane glycoprotein 80

Poids moléculaire: 37.9 kDa

UniProt: P08887

Pathways: Signalistation JAK/STAT, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints