IL16 Protéine

N° du produit ABIN2830830

Cette protéine Recombinant IL16 est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour IL16 Protéine (ABIN2830830)

Antigène: IL16 (Interleukin 16 (IL16))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Macaque rhésus

Source: Escherichia coli (E. coli)

Application: Functional Studies (Func)

Pureté: >98 % as determined by SDS-PAGE and HPLC.

Détail du produit

Séquence: SAASASAASD VSVESSAEAT VYTVTLEKMS AGLGFSLEGG KGSLHGDKPL TINRIFKGAA SEQSETIQPG DEILQLAGTA MQGLTRFEAW NIIKALPDGP VTIVIRRKSL QPKETTAAAD S

Attributs du produit: Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral T lymphocytes is in a concentration range of 1.0-100 ng/mL.

Stérilité: 0.2 μm filtered

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Détail du antigène

Antigène: IL16 (Interleukin 16 (IL16))

Autre désignation: IL16

Sujet: Relevance: Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4 (By similarity). {ECO:0000250}., Pro-interleukin-16 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells (By similarity). {ECO:0000250}.
Synonyms: IL-16, LCF,]

Poids moléculaire: 12.5 kDa

UniProt: O62675