Haptoglobin Protein (HP)
Aperçu rapide pour Haptoglobin Protein (HP) (ABIN2869535)
Antigène
Voir toutes Haptoglobin (HP) ProtéinesType de proteíne
Origine
Source
Pureté
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Attributs du produit
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Purified native Human Haptoglobin protein
Protein Source: Human plasma
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Reconstitution
- Reconstitute with 1.0 mL of PBS, pH 7.4, per 1.0 mg of antigen.
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Buffer
- Supplied as a lyophilised powder.
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Précaution d'utilisation
- Donor samples were tested and found to be negative for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot and store at -20 °C.
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- Haptoglobin (HP)
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Autre désignation
- Haptoglobin
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Sujet
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An acute-phase plasma protein found in human plasma at 100-300 mg per 100 ml. Binds hemoglobin, thus preventing loss of iron through the kidneys. Humans are polymorphic for haptoglobin, with three major phenotypes. Hp 1-1 is the most common, and the most effective in binding free hemoglobin. Hp 2-2 is the least effective. This functional difference may be associated with the frequency and severity of epilepsy attacks, as researchers have found a correlation between recurring seizures and the Hp 2-2 phenotype.
Description: Human plasma.
Alternative Names: HP protein, Haptoglobin, HPT protein, beta polypeptide protein, HP2 alpha2 protein, Haptoglobin protein, MGC111141 protein, HPA1S protein, alpha polypeptide protein, Hp2 alpha protein -
Poids moléculaire
- Hp 1-1: 86 kDa, Hp 2-1: 200 kDa, Hp 2-2: 400 kDa
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Pathways
- Transition Metal Ion Homeostasis
Antigène
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