Deoxyguanosine Kinase Protein (DGUOK) (His tag)

N° du produit ABIN5505615

Cette protéine Recombinant Deoxyguanosine Kinase est produite dans Escherichia coli (E. coli).

Aperçu rapide pour Deoxyguanosine Kinase Protein (DGUOK) (His tag) (ABIN5505615)

Antigène: Deoxyguanosine Kinase (DGUOK)

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: Antibody Production (AbP), Standard (STD)

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Détail du produit

Purification/Conjugué: Cette Deoxyguanosine Kinase protéine est marqué à la His tag.

Attributs du produit:

• Recombinant human Purified recombinant protein of Human deoxyguanosine kinase (DGUOK), nuclear gene encoding mitochondrial protein, transcript variant 2, full length, with N-terminal HIS tag, expressed in E.coli, 50 μg (full length, N-term HIS tag, transcript variant 2) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Purification: Purified

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 50 mM Tris, 8M Urea, pH 8.0

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Deoxyguanosine Kinase (DGUOK)

Autre désignation: deoxyguanosine kinase

Sujet: In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.

Poids moléculaire: 17.3 kDa

NCBI Accession: NP_550440

Pathways: Ribonucleoside Biosynthetic Process