Deoxyguanosine Kinase Protein (DGUOK) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2719393

Détail du produit

Antigène: Deoxyguanosine Kinase (DGUOK)

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Deoxyguanosine Kinase protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Deoxyguanosine kinase (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Deoxyguanosine Kinase (DGUOK)

Autre désignation: Deoxyguanosine Kinase (DGUOK Produits)

Synonymes: DGUOK Protein, zgc:86625 Protein, dgk Protein, DDBDRAFT_0218264 Protein, DDBDRAFT_0233982 Protein, DDB_0218264 Protein, DDB_0233982 Protein, MTDPS3 Protein, dGK Protein, dGK1 Protein, dGK2 Protein, dGK3 Protein, deoxyguanosine kinase Protein, deoxyguanosine kinase L homeolog Protein, DGUOK Protein, dguok Protein, dguok.L Protein, dgk Protein, Ccan_04750 Protein, Dguok Protein

Sujet: In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.

Poids moléculaire: 27.9 kDa

NCBI Accession: NP_550438

Pathways: Ribonucleoside Biosynthetic Process