CD28 Protein (CD28) (partial) (His tag)
Aperçu rapide pour CD28 Protein (CD28) (partial) (His tag) (ABIN5608228)
Antigène
Voir toutes CD28 ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Attributs du protein
- partial
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Purification/Conjugué
- Cette CD28 protéine est marqué à la His tag.
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Séquence
- Asn 20 - Lys 149
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niveau d'endotoxine
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
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Indications d'application
- This recombinant protein can be used for WB.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- CD28
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Autre désignation
- CD28
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Sujet
- T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
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Poids moléculaire
- 17 kDa
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ID gène
- 12487
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NCBI Accession
- NP_031668
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UniProt
- P31041
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Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Antigène
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