CD47 Protein (CD47) (partial) (Fc Tag)
Aperçu rapide pour CD47 Protein (CD47) (partial) (Fc Tag) (ABIN5608234)
Antigène
Voir toutes CD47 ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Attributs du protein
- partial
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Purification/Conjugué
- Cette CD47 protéine est marqué à la Fc Tag.
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Séquence
- Gln 19 - Lys 140
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niveau d'endotoxine
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
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Indications d'application
- This recombinant protein can be used for WB.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 50 mM Tris, 100 mM Glycine, pH 7.5
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- CD47
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Autre désignation
- CD47
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Sujet
- Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.
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Poids moléculaire
- 40.4 kDa
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ID gène
- 29364
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UniProt
- P97829
Antigène
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