Hemopexin Protein (HPX)

N° du produit ABIN5662823

Détail du produit

Antigène: Hemopexin (HPX)

Type de proteíne: Native

Origine: Humain

Source: Human

Réactivité croisée (Details): Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Pureté: >95 %

Information d'application

Indications d'application: For use in: SDS

Commentaires:

Extinction Coefficient: 1.97

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 11.9 mM phosphate, 137 mM NaCl, 2.7 mM KCl, pH 7.4.

Stock: -20 °C

Stockage commentaire: -20°C

Référence

Kozlik, Sanda, Goldman: "Nano reversed phase versus nano hydrophilic interaction liquid chromatography on a chip in the analysis of hemopexin glycopeptides." dans: Journal of chromatography. A, Vol. 1519, pp. 152-155, (2017) (PubMed).

Kozlik, Goldman, Sanda: "Study of structure-dependent chromatographic behavior of glycopeptides using reversed phase nanoLC." dans: Electrophoresis, Vol. 38, Issue 17, pp. 2193-2199, (2017) (PubMed).

Sakamoto, Kim, Hara, Kamada, Caballero-Flores, Tolosano, Soares, Puente, Inohara, Núñez: "IL-22 Controls Iron-Dependent Nutritional Immunity Against Systemic Bacterial Infections." dans: Science immunology, Vol. 2, Issue 8, (2017) (PubMed).

Aggarwal, Lam, Bolisetty, Carlisle, Traylor, Agarwal, Matalon: "Heme Attenuation Ameliorates Irritant Gas Inhalation-Induced Acute Lung Injury." dans: Antioxidants & redox signaling, Vol. 24, Issue 2, pp. 99-112, (2016) (PubMed).

Mehta, Grijalva, Hama, Wagner, Navab, Fogelman, Reddy: "Apolipoprotein E-/- Mice Lacking Hemopexin Develop Increased Atherosclerosis via Mechanisms That Include Oxidative Stress and Altered Macrophage Function." dans: Arteriosclerosis, thrombosis, and vascular biology, Vol. 36, Issue 6, pp. 1152-63, (2016) (PubMed).

Kassa, Jana, Meng, Alayash: "Differential heme release from various hemoglobin redox states and the upregulation of cellular heme oxygenase-1." dans: FEBS open bio, Vol. 6, Issue 9, pp. 876-84, (2016) (PubMed).

Lin, Liu, Huang, Van Engelen, Thundivalappil, Riley, Super, Watters, Smith, Brinkman, Ingber, Warren: "Purified and recombinant hemopexin: protease activity and effect on neutrophil chemotaxis." dans: Molecular medicine (Cambridge, Mass.), (2016) (PubMed).

Kassa, Jana, Strader, Meng, Jia, Wilson, Alayash: "Sickle Cell Hemoglobin in the Ferryl State Promotes βCys-93 Oxidation and Mitochondrial Dysfunction in Epithelial Lung Cells (E10)." dans: The Journal of biological chemistry, Vol. 290, Issue 46, pp. 27939-58, (2015) (PubMed).

Détail du antigène

Antigène: Hemopexin (HPX)

Autre désignation: Hemopexin (HPX Produits)

Synonymes: HPX Protein, HX Protein, Hpxn Protein, hx Protein, wu:fi17f11 Protein, wu:fi19a10 Protein, hemopexin Protein, HPX Protein, Mmar10_1124 Protein, Hpx Protein, hpx Protein

Sujet: HPX, HX, Hpxn, beta-1B-glycoprotein, transporter

Poids moléculaire: 57 kDa

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response