WT1 Protein (AA 1-449, full length)
Aperçu rapide pour WT1 Protein (AA 1-449, full length) (ABIN5710628)
Antigène
Voir toutes WT1 ProtéinesType de proteíne
Origine
Source
Application
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Attributs du protein
- AA 1-449, full length
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Fonction
- Recombinant Human Wilms tumor protein(WT1)
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.1-2 mg/mL
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
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Date de péremption
- 6-12 months
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- WT1 (Wilms Tumor 1 (WT1))
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Autre désignation
- WT1
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Sujet
- Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital syst. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.
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Pathways
- Tube Formation
Antigène
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