Biglycan Protein (BGN) (AA 38-369) (hIgG-His-tag)
Aperçu rapide pour Biglycan Protein (BGN) (AA 38-369) (hIgG-His-tag) (ABIN5855132)
Antigène
Voir toutes Biglycan (BGN) ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Attributs du protein
- AA 38-369
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Purification/Conjugué
- Cette Biglycan protéine est marqué à la hIgG-His-tag.
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Séquence
- ADPDEEASGS DTTSGVPDLD SVTPTFSAMC PFGCHCHLRV VQCSDLGLKT VPKEISPDTT LLDLQNNDIS ELRKDDFKGL QHLYALVLVN NKISKIHEKA FSPLRKLQKL YISKNHLVEI PPNLPSSLVE LRIHDNRIRK VPKGVFSGLR NMNCIEMGGN PLENSGFEPG AFDGLKLNYL RISEAKLTGI PKDLPETLNE LHLDHNKIQA IELEDLLRYS KLYRLGLGHN QIRMIENGSL SFLPTLRELH LDNNKLSRVP AGLPDLKLLQ VVYLHSNNIT KVGINDFCPM GFGVKRAYYN GISLFNNPVP YWEVQPATFR CVTDRLAIQF GNYKKLEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSRDELT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGKHH HHHH
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niveau d'endotoxine
- < 1 EU per 1ug of protein (determined by LAL method)
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Biglycan (BGN) (AA 1-368) protein (GST tag)
BGN Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Biglycan (BGN) protein (Fc Tag)BGN Origine: Souris Hôte: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
Biglycan (BGN) (AA 38-368) (Active) protein (His tag)BGN Origine: Humain Hôte: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, WB, Imm, ELISA, AcA Active
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Biglycan (BGN)
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Autre désignation
- Biglycan
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Sujet
- Bgn, also known as biglycan preproprotein, is a small leucine-rich repeat proteoglycan (SLRP). It binds to the growth factors BMP-4 and influences BMP-4 bioactivity. It plays an important role in stabilizing fibrotic scars after experimental myocardial infarction. It may function in connective tissue metabolism by binding to collagen fibrils and TGF-beta and may promote neuronal survival. Its ablation improves cardiac function and attenuates left ventricular hypertrophy and fibrosis after long-term pressure overload. It is found in a variety of extracellular matrix tissues, including bone, cartilage and tendon. Recombinant mouse Bgn, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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Poids moléculaire
- 64.6 kDa (574aa)
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NCBI Accession
- NP_031568
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UniProt
- P28653
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Pathways
- Glycosaminoglycan Metabolic Process
Antigène
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