Transferrin Protein (TF) (full length)

N° du produit ABIN7479567

Cette protéine Native Transferrin est exprimée dans .

Aperçu rapide pour Transferrin Protein (TF) (full length) (ABIN7479567)

Antigène: Transferrin (TF)

Type de proteíne: Native

Origine: Humain

Hôte: Veuillez nous consulter SVP

Application: Western Blotting (WB), ELISA

Pureté: > 90 %(SDS-PAGE)

Détail du produit

Attributs du protein: full length

Attributs du produit: Full length native Human Transferrin

Purification: Purified from Human plasma

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS

Détail du antigène

Antigène: Transferrin (TF)

Autre désignation: Transferrin protein

Sujet: Background: Transferrin is a single polypeptide chain glycoprotein and is a member of the iron binding family of proteins. It has a molecular weight of 77 kDa and a serum concentration range of 1800 to 2700 mg/L. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. Iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. The function of transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. In addition to its function in iron transport, this protein may also have a physiologic role as granulocyte/pollen binding protein (GPBP) involved in the removal of certain organic matter/allergens from serum. Synonyms: Serotransferrin, Beta-1 metal-binding globulin, Siderophilin.

Pathways: Transition Metal Ion Homeostasis