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CD52 Protein (CD52) (AA 25-36) (hIgG-His-tag)

Cette protéine Recombinant CD52 est exprimée dans Baculovirus infected Insect Cells.
N° du produit ABIN6388178

Aperçu rapide pour CD52 Protein (CD52) (AA 25-36) (hIgG-His-tag) (ABIN6388178)

Antigène

Voir toutes CD52 Protéines
CD52

Type de proteíne

Recombinant

Origine

  • 10
  • 2
Humain

Source

  • 8
  • 1
  • 1
  • 1
  • 1
Baculovirus infected Insect Cells

Application

SDS-PAGE (SDS)

Pureté

> 95% by SDS-PAGE
  • Attributs du protein

    AA 25-36

    Purification/Conjugué

    Cette CD52 protéine est marqué à la hIgG-His-tag.

    Séquence

    GQNDTSQTSS PSLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H

    niveau d'endotoxine

    < 1 EU per 1ug of protein (determined by LAL method)
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  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.5 mg/mL

    Buffer

    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

    Stock

    4 °C,-20 °C,-80 °C

    Stockage commentaire

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • Antigène

    CD52

    Autre désignation

    CD52

    Sujet

    CD52, also known as CAMPATH-1 antigen, is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein that is tethered to the cell surface with a GPI linkage. This protein can be targeted to induce immune suppression by complement-meditated cell lysis. CD52 is expressed on lymphocytes, monocytes, monocytes-derived dendritic cells, eosinophils, and neutrophils, but not on the stem cells from which these lymphocytes were derived. Also, it is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. Recombinant human CD52, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

    Poids moléculaire

    28.2 kDa (251aa)

    NCBI Accession

    NP_001794

    UniProt

    P31358
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