STIM1 Protein (AA 23-213) (Calmodulin (CaM))

N° du produit ABIN666653

Cette protéine Recombinant STIM1 est produite dans Escherichia coli (E. coli).

Aperçu rapide pour STIM1 Protein (AA 23-213) (Calmodulin (CaM)) (ABIN666653)

Antigène: STIM1 (Stromal Interaction Molecule 1 (STIM1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Pureté: > 90 %

Détail du produit

Attributs du protein: AA 23-213

Purification/Conjugué: Cette STIM1 protéine est marqué à la Calmodulin (CaM).

Séquence: MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQVNYE EFVQMMTAKG SMLSHSHSEK ATGTSSGANS EESTAAEFCR IDKPLCHSED EKLSFEAVRN IHKLMDDDAN GDVDVEESDE FLREDLNYHD PTVKHSTFHG EDKLISVEDL WKAWKSSEVY NWTVDEVVQW LITYVELPQY EETFRKLQLS GHAMPRLAVT NTTMTGTVLK MTDRSHRQKL QLKALDTVLF GPPLLTRHNH LKD

Attributs du produit: STIM1, 23-213aa, Human, CaM tagged, Recombinant, E.coli

Purification: > 90% by SDS-PAGE

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 7.5)

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: STIM1 (Stromal Interaction Molecule 1 (STIM1))

Autre désignation: STIM1

Sujet: Stromal interaction molecule 1 (STIM1) is a transmembrane protein that is essential for store-operated Ca (2+) entry, a process of extracellular Ca (2+) influx in response to the depletion of Ca (2+) stores in the endoplasmic reticulum (ER). STIM1 localizes predominantly to the ER, upon Ca (2+) release from the ER, STIM1 translocates to the ER-plasma membrane junctions and activates Ca (2+) channels. Recombinant Calmodulin tagged STIM was expressed in E. coli and purified by using conventional chromatography techniques.

Poids moléculaire: 38 kDa (343aa) confirmed by MALDI-TOF

NCBI Accession: NP_003147

Pathways: TCR Signaling, BCR Signaling